L1in2years Pasteur

Semester 1

• From the atom to the molecule (6 ECTS)
• Living World (4 ECTS)
• Mathematical Tools (4 ECTS)
• Methodology (3 ECTS)

Semester 2

• Thermochemistry and Solution Chemistry (6 ECTS)
• Physics 1: Optics and Electricity (3 ECTS)
• English (3 ECTS)
• 3PE : Student's Personal and Professional Project (3 ECTS)
• Mathematical tools - complements

Semester 3

• Biochemistry: the molecules of life (6 ECTS)
• Habitable Earth (4 ECTS)
• The major current issues of our society (3 ECTS)
• Mathematical tools - complements
• English - complements

Semester 4

• Discovery project (3 ECTS)
• Advanced discoveries 1 : Cellular Biology, Statistics, Mechanics and Thermodynamics, or Physics and Chemistry for Agro/Véto exam (4 ECTS)
• Advanced Discoveries 2 : Anatomy, Molecular Architecture, Statistics or General Culture for Agro/Véto exam (4 ECTS)
• Advanced Discoveries 3 : Molecular Biology, Society & Health, Math for Chemistry, Math for Agro/Vet competition, or Geological Practice (4 ECTS)
• PES option for further studies: Chemistry, Biochemistry, Entrepreneurship

The fundamental and theoretical elements will be apprehended in Amphi in the form of lectures. This knowledge will then be used during two sessions of TD (2 hours each) and two sessions of TP (2 hours each).

Program :

Biomes / Three domains of life / Phylogeny / Archaea-bacteria-viruses / Evolution / Opistho / Plants / Plants-pollinators / Parasites

Atomistics" part

Spectrum of the hydrogen atom. Brief description of atomic orbitals. Atomic electronic configurations. Periodic properties. Lewis model. Molecular orbital diagrams for diatomic molecules.

Part "Molecules

Writing and representation of molecules (Cram, Newman, Fisher), geometry of molecules, different types of isomerism, conformational analysis, stereodescriptors (Z/E, cis/trans, R/S, D/L), chirality and optical activity, enantiomerism, diastereomerism, principle of nomenclature, functions of organic chemistry

Elementary tools of analysis: real functions in one and two real variables, integration and differential equations.

• Chapter 1: Real functions of one real variable
• Chapter 2: Calculation of primitives
• Chapter 3: Differential equations
• Chapter 4: Real functions in two real variables

To inform students about their brain functioning and the effects of context during learning, revision, during an exam, so that they can :

1. reflect on their knowledge, on the effectiveness of their learning and revision methods, on their motivations
2. understand the reasoning they use to solve complex problems
3. deconstruct (when necessary) some of the misconceptions about their abilities, efforts and work;
4. managing the stress of certain assessment situations;
5. develop effective working methods (knowledge and know-how), taking into account the functioning of the memory, and postures (life skills) adapted to improve their learning and the development of the competencies targeted by the training they have chosen. Apply this learning to revisit fundamental disciplinary or interdisciplinary notions for L1.

Part "Solution Chemistry

• Introduction: Solvent, molar and mass concentrations, chemical reaction, thermodynamic constant, notion of equilibrium, progress.
• Acid-Base: Acid-base equilibria. Acid-base couple. Acid-base pairs of water. Acid-base reaction. Acidity constant of a couple in aqueous solution, pKa, pKb). Domains of predominance of acid-base species as a function of pH. pH of aqueous acid-base solutions. Calculation of pH of monoacids in water, monobases in water, ampholyte. Metric and colorimetric pH titration of monoacids or monobases. Buffer solutions.
• Precipitation: Precipitation equilibria. Precipitation condition, precipitation equilibrium and solubility constant (or solubility product). Different factors influencing solubility.
• Redox reactions:
• Redox equilibria: redox couple. Electrochemical cells: concept of electrode potential. Standard hydrogen electrode. Standard potentials. Nernst formula.
• Potential-pH diagrams: emphasis will be placed on the interpretation of these diagrams rather than on their construction.
• Prediction of a redox reaction: domains of predominance of the oxidant and reductant as a function of potential. Application to the prediction of a redox reaction, application to corrosion risks.

Part "Thermochemistry

From the first two principles applied to chemical reactions, to equilibria (inclusive).

• Geometrical optics: light, optical index and light ray. Plane mirror, Snell-Descartes laws. Formation of images through an optical system, thin lenses and the conjugation relation.
• Electricity: The electric circuit and its dipoles, voltage and current, Kirchhoff's laws. Resistance and resistivity, Ohm's law, combination of resistors. Capacitor and capacitor, RC circuit, charge and discharge.
• Optics lab: thin lenses, eye at rest and microscope
• Electrical lab: voltage divider bridge, oscilloscope, RC circuit

The aim will be to use active pedagogical methods to practice the English language, both orally and in writing, through activities such as drawing up a protocol or writing a report. Thus, we will build a practice of physics around the uncertainties in the measurements with a specialized and scientific vocabulary.

To discover the training courses and the professional fields concerned accessible at the end of the portal and the licence. To engage in personal reflection based on one's own project - Methodology of documentary research.

• Development of the map of professions and methodology of interview grids.
• Development of the personal and professional project
• Discovery of the fields of study after L1
• Individual interview at the end of the semester on the student's project

Introduction: spirit of the course

• How have the great forces of the universe shaped our solar system and how do they impact the earth system?
• How do time and space affect the dynamics of the solar system and Earth?
• How is the Earth different from the other planets in the Earth system?
• Why does the Earth have solid and liquid shells and how are they arranged?
• Why and how did life arise on Earth? Why is life not fixed?
• Why is the surface of our planet habitable when it is changing?
• How does the climate sustain life and how does it interact with the evolution of the Earth system?
• How can we tell the story of the Earth and its evolution?
• How can we maintain a habitable planet? Vulnerability
• How can a habitable planet be maintained? Resource
• How can we maintain a habitable planet? Modern Issues

TD Sessions:

• I live in a solar system
• Rock Matter
• Reversing time and reading rocks
• Story of a Grain of Sand
• Risk on the Ground
• Exploring the underground
• Climate in danger

This course will be done in the form of an integrated practical course.

• Introduction to biology manipulation: Use of pipettes, preparation of a solution, dilution, preparation of a buffer
• Biochemistry: Chromatography, dosing
• Molecular biology: DNA extraction/visualization, PCR/restriction enzyme cutting
• Cell biology: microscopic observation of tissue slides.
• Physiology: cardiovascular system

This teaching is centered on a theme related to one or more of the major scientific disciplines of biology, geology, ecology and environmental chemistry. On these themes, students will put into practice the knowledge acquired in secondary education and in semester 1. They will thus be able to verify their degree of assimilation and understanding of this knowledge. This teaching will also be an approach to scientific practice with its requirements: definition and analysis of the proposed work, modelling effort, exploration of the various strategies and choice of the one that seems best adapted, scientific and technical documentation, organisation and distribution of technical measurement tasks, precision, critical exploitation and presentation of the results, group work, writing of a report, realisation of a poster or a slide show and presentation of scientific work orally. This encounter with the different facets of scientific practice should help the student to better situate himself in his training project and to specify his orientation towards one of the courses of the four bachelor's degrees.

The objective of the "Discovery of SSS" course is to get students to work in groups on subjects related to the disciplines taught in the Health and Social Sciences degree.

For this, students will work in groups of 5 on one of the topics proposed during the 1st session. They will then be accompanied in their research during the tutoring sessions.

The courses are held in English and are based on interaction between students, solicited and guided by the teachers. The themes studied are approached through a variety of written, audio and video documents, recent and authentic, accessible on the AMeTICE platform and the students' activities aim to reinforce their skills through practice. Digital support materials are made available to students for their self-learning.

The aim of this Structural Biochemistry course is to familiarize the student with the constituents of living matter: their chemical structure and their function. This knowledge is essential to understand the specificity of life compared to the mineral world and to explain the functioning of the cell and living organisms. This knowledge will therefore be essential to follow, in good conditions, the different courses of the Life Sciences Licence. They will also be very useful for the SVT, SSS and Chemistry degrees.